SERVICES
We work closely together with clients to design the strategy and generate customized engineering vectors to best fit their experimental needs and the characteristics of specific cell types. Engineered cells are guaranteed to pass our rigorous QC assays to verify the desired modifications.
CRISPR knockout (KO) services offer a powerful and precise approach to gene editing, enabling researchers to investigate gene function by selectively disabling specific genes in cells or organisms. Leveraging the revolutionary CRISPR-Cas9 technology, our services provide customized solutions for generating stable knockout models with high efficiency and specificity. From guide RNA design to validation of gene disruptions, our expert team ensures reliable, reproducible results tailored to your research needs, accelerating discoveries in functional genomics, disease modeling, and therapeutic development.
CRISPR Gene
Knock-out
CRISPR Gene
Knock-in
CRISPR knock-in services provide a cutting-edge solution for precise gene editing, enabling researchers to insert specific DNA sequences or induce point mutation into targeted genomic loci. Utilizing the advanced CRISPR-Cas9 system, our services facilitate the creation of custom knock-in models with unparalleled accuracy and efficiency. From designing donor templates to validating successful integrations, our expert team delivers tailored solutions to support your research in functional genomics, disease modeling, and therapeutic development, empowering breakthrough discoveries with reliable and reproducible results.
Gene overexpression services offer a robust approach to studying gene function by enabling researchers to increase the expression levels of specific genes in cells or organisms. Utilizing advanced molecular biology techniques, our services provide customized solutions (constitutive expression, inducible expression, etc.) for generating stable overexpression models with high efficiency using viral (lentivirus, etc.) or non-viral (conventional plasmid transfection, transposase-based transduction, etc.) approaches. From vector design to validation of elevated gene expression, our expert team delivers tailored support to accelerate your research in functional genomics, pathway analysis, and therapeutic development, ensuring reliable and impactful results.
Constitutive
Expression
Inducible
Expression
iPSC Editing
Induced Pluripotent Stem Cell (iPSC) editing services provide a transformative platform for precise genetic modifications, empowering researchers to explore cellular mechanisms and disease modeling with unparalleled flexibility. Leveraging advanced CRISPR-Cas9 and other gene-editing technologies, our services offer customized solutions for generating edited iPSC lines with high efficiency and accuracy. From guide RNA design to validation of genetic alterations, our expert team delivers tailored support to advance your research in regenerative medicine, developmental biology, and therapeutic discovery, ensuring robust and reproducible outcomes.
Primary immune cell editing services offer a cutting-edge approach to modifying immune cells with precision, enabling researchers to investigate immune function, develop novel immunotherapies, and model immune-related diseases. Utilizing advanced gene-editing technologies such as CRISPR-Cas9, our services provide customized solutions for editing primary immune cells with high efficiency and specificity. From experimental design to validation of genetic modifications, our expert team delivers tailored support to accelerate breakthroughs in immunology, cell therapy, and translational research, ensuring reliable and impactful results.
Primary Immune
Cell Editing
Other Capabilities
-
Cell-based assay design and testing (transfection, nucleofection, virus infection, LNP, CRISPR screening, etc.)
-
Protein or DNA/RNA extraction: from cells in various formats (tubes, strips, or 96-well plates) to in vivo tissue samples.
-
Downstream analysis: RT-qPCR, ELISA, Western Blot, FACS, Sequencing (Sanger, short-read/long-read NGS sequencing, RNAseq, scRNAsec, WGS, etc.)
-
Virus packaging (lentivirus and AAV)
-
And more...